Updated : September 27, 2023

Embryology

Supervisors

Kazuki Kurimoto (Professor)

Hisato Kobayashi (Associate Professor)

So Nagaoka (Assistant Professor)

Hiroki Ikeda (Assistant Professor)

Specialized Subjects

The primary objective of our research group is to gain a comprehensive understanding of the genomic regulatory mechanisms underlying the developmental potential of germ cells and the transmission of genomic and epigenomic information across generations. To achieve this goal, we are actively involved in the development of advanced genomic analytical methods specifically designed for in vitro contexts. This includes the development of techniques for analyzing single cells isolated from tissue sections (spatial transcriptomics).

Additionally, we are dedicated to the development of in vitro gametogenesis systems utilizing human and mouse pluripotent stem cells. Moreover, we are working on the establishment and refinement of ovarian organoids, which provide a valuable platform to investigate the complex interactions and developmental processes within the ovary.

By combining these analytical and synthetic approaches, we aim to uncover key insights into the intricate genomic regulatory mechanisms governing germ cell development and the inheritance of genomic and epigenomic information. Ultimately, our research endeavors contribute to advancing our understanding of reproductive biology and have the potential to advance assisted reproductive technologies and fertility preservation.

Website

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